Tirzepatide is administered as a once-weekly subcutaneous (under the skin) injection. You can inject it in areas such as the abdomen, thigh, or upper arm. Your nurse injector will teach you the correct injection technique, as well as how to handle and store the medication properly.

Typically comes as a once-weekly subcutaneous injection (under the skin) using a pen-like device or syringe. Injections can be given in the abdomen, thigh, or upper arm.

By increasing feelings of fullness, slowing stomach emptying, and helping to control appetite, semaglutide supports calorie reduction and, combined with a healthy diet and exercise, can lead to gradual, sustained weight loss

Gastrointestinal issues—such as nausea, vomiting, or diarrhea—are the most common side effects, especially when starting treatment. Other possible side effects include decreased appetite, headache, and fatigue. Serious side effects are very rare but can include pancreatitis or thyroid tumors.

Keep semaglutide syringes refrigerated until first use, then store them at room temperature if the manufacturer’s instructions permit. Always protect syringes from direct sunlight and do not use them past their expiration date.

Semaglutide and Tirzepatide is often a long-term therapy. For diabetes management, you’ll likely need ongoing treatment. For weight loss, if you stop taking it, the appetite-suppressing effects will diminish, and weight regain can occur without continued lifestyle measures.

If you miss a dose, take it as soon as you remember, provided the next scheduled dose is at least two days away. If it’s closer to your next dose, skip the missed dose and return to your regular schedule. Do not take extra doses to make up for a missed one.