Platelet Rich Fibrin Matrix (PRFM) Under Eye Injections in St. Louis, MO

The quest for youthful, rejuvenated skin leads many people to explore innovative cosmetic treatments. One such cutting-edge therapy is Platelet-Rich Fibrin (PRF) Matrix, which has recently gained attention as a minimally invasive solution for under-eye concerns. If you’ve been dealing with dark circles, fine lines, or hollowness beneath the eyes, PRFM might just be the natural boost you’ve been looking for.

What is Platelet-Rich Fibrin Matrix (PRFM)?

Platelet-Rich Fibrin Matrix (PRFM) is a natural byproduct of your own blood that is rich in platelets, growth factors, and fibrin. Unlike Platelet-Rich Plasma (PRP), PRFM is obtained using a slightly different processing technique that involves a slower centrifugation and the absence of anticoagulants. This results in a higher concentration of growth factors, which are released gradually over time to accelerate the healing process and stimulate collagen production in the treated area.

When used in cosmetic procedures, PRF helps encourage tissue regeneration, increased blood flow, and collagen synthesis, all of which can lead to smoother, brighter, and more supple skin under the eyes.

How is the PRFM Under-Eye Procedure Done?

  • Blood Draw: The procedure starts with drawing a small sample of your blood—similar to what you’d experience during routine lab work.
  • Centrifugation: The vial of blood is then placed in a specialized centrifuge. This device spins the blood at a lower speed (compared to PRP preparation) and for a specific duration. The goal is to separate out the platelet-rich fibrin without adding anticoagulants.
  • Fibrin Matrix Collection: The tube is removed from the centrifuge, and the PRF layer (a gel-like substance) is carefully extracted.
  • Under-Eye Injection: A skilled practitioner then injects or uses microcannulas to place the PRFM into the under-eye region. Because the treatment utilizes your own blood components, the risk of allergic reactions is minimal.
  • Post-Procedure Protocol: After your treatment, you may be given post-care instructions, such as avoiding intense physical activity, refraining from using certain topical products, or applying cold compresses to minimize swelling.

What is PRFM Used For Under the Eyes?

  • Reducing Dark Circles: Dark circles can be caused by thinning skin and poor circulation. PRFM injections aim to strengthen the tissue and increase vascularity, helping lighten the under-eye area.
  • Minimizing Fine Lines and Wrinkles: Growth factors in PRFM stimulate collagen production, which helps plump the skin and reduce the appearance of fine lines.
  • Improving Hollowness: By adding volume and promoting tissue regeneration, PRFM can help fill in tear trough depressions, creating a smoother contour under the eyes.

Who is a Candidate for PRF Under the Eyes?

Almost any adult with mild to moderate under-eye concerns such as dark circles, fine lines, or hollowness could benefit from PRFM. It’s particularly appealing for individuals who:

  • Prefer a more natural approach, as PRFM utilizes the body’s own regenerative components.
  • Are not candidates for dermal fillers or who have had adverse reactions to synthetic injectables in the past.
  • Desire a minimal-downtime procedure.
  • Want to complement other cosmetic treatments like microneedling or laser therapy.

However, PRFM may not be the best option for those with severe volume loss, heavy under-eye bags, or certain medical conditions. 

Side Effects and Risks

Because PRFM is derived from your own blood, there is a low risk of allergic reaction or rejection. Still, as with any injection, you can experience:

  • Mild Swelling and Bruising: The under-eye area is sensitive, so some bruising is possible.
  • Temporary Redness or Discomfort: Injection sites may feel tender for a day or two.
  • Minimal Downtime: Most people can resume normal activities the same day or the next.

Benefits of PRF for Under-Eye Rejuvenation

  • Natural Approach: By harnessing the regenerative power of your own blood, you reduce exposure to synthetic substances.
  • Long-Lasting Results: Growth factors are released gradually, which can lead to sustained tissue improvement over several weeks or months.
  • Boosted Collagen and Elastin Production: Healthier skin structure means a more youthful and vibrant appearance over time.
  • Minimal Downtime: Most patients only experience mild swelling or bruising that fades within a few days.
  • Versatility: PRFM can be used not only under the eyes but also in combination with other treatments to enhance overall facial rejuvenation.

General Questions

  • How many sessions will I need? While some patients notice improvements after one session, many providers suggest 2-3 treatments spaced 4-6 weeks apart for optimal results. Each individual’s response can vary based on factors like skin quality and treatment goals.
  • Is the procedure painful? You may feel mild discomfort or a pinch during the blood draw and the injections. Most practitioners use a topical numbing cream or other pain management techniques to ensure your comfort.
  • How soon will I see results? You might observe subtle improvements in skin texture and brightness within the first few weeks. Because PRFM works by stimulating your body’s natural rejuvenation processes, the full effect often becomes more evident 6-8 weeks post-treatment.
  • Can I combine PRF with other treatments? Absolutely. PRFM is frequently combined with microneedling, chemical peels, laser therapies, or dermal fillers for enhanced facial rejuvenation. Discuss a combined treatment plan with your provider to address all your cosmetic concerns holistically.
  • Is PRFM better than PRP? They are similar but not identical. PRFM (Platelet-Rich Fibrin) generally contains higher concentrations of platelets and growth factors released over a longer period, which may offer more sustained benefits. However, PRP remains a popular treatment and can be more suitable in certain cases. Your provider can recommend the best option for your specific needs.
  • What if I have a medical condition? It’s important to discuss your medical history and any medications you’re taking with your provider. Certain autoimmune conditions, blood disorders, or medications (e.g., blood thinners) could affect whether PRFM is right for you.
  • How long do results last? Results can last several months to a year or more, depending on factors like age, lifestyle, and skin type. Many people opt for maintenance treatments once or twice a year to preserve their results.

Platelet-Rich Fibrin Matrix (PRFM) therapy for the under-eye area represents a promising, natural solution to common aesthetic concerns such as dark circles, fine lines, and hollowness. With minimal downtime, long-lasting effects, and low risk of adverse reactions, PRFM has become a go-to option for those seeking a gentle but effective facial rejuvenation method.

If you’ve been searching for a non-surgical, natural approach to banish under-eye woes, reach out for a consultation with one of The Saint Louis Med Spa’s nurse injectors about PRFM treatments. As with any procedure, ensure you receive a thorough evaluation and understand your personalized treatment plan before moving forward.

Benefits of Platelet Rich Fibrin Matrix (PRFM) for Under Eye

  • Natural, Regenerative Approach - PRFM is created from your own blood, reducing the risk of allergic reactions or rejection. Growth factors in the platelet-rich fibrin help stimulate collagen and elastin production—integral proteins for skin firmness and elasticity.
  • Improved Under-Eye Volume and Texture - By boosting collagen synthesis, PRFM can help fill in hollows under the eyes (the tear trough area), giving a smoother, more youthful look.
  • Reduction in Dark Circles and Fine Lines - PRFM can help diminish the appearance of dark under-eye circles by improving circulation and skin health in that region. The increased collagen and tissue repair may also soften the look of fine lines and wrinkles around the eyes.
  • Long-Lasting Results - While individual results vary, the regenerative effects of PRFM can last longer compared to some other aesthetic treatments because it helps your body heal and rejuvenate from within.
  • Minimal Downtime and Low Risk Profile - Since PRFM involves injecting your own biological material, adverse reactions tend to be minimal compared to synthetic fillers. Recovery time is generally short; patients may experience mild swelling or bruising at the injection site but can typically resume normal activities quickly.
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Platelet Rich Fibrin Matrix (PRFM) Uner Eye Injections

Frequently Asked Questions

What Is PRFM?

PRFM stands for platelet-rich fibrin matrix, it uses platelets and natural growth factors taken from a patient's blood to rejuvenate their skin.

What Conditions Can PRFM Address?

PRFM is often used for facial rejuvenation and hair restoration.

Is PRFM Therapy Safe?

Yes. Because PRFM is derived from your own blood (autologous treatment), the risk of allergic reaction or rejection is extremely low.

How Many PRFM Sessions Are Needed?

Treatment protocols vary based on the condition being addressed, but most services range between 3-4 sessions.

When Will I See Results?

Typically 2-4 weeks for skin rejuvenation and 3-6 months for hair restoration.

How Long Do the Effects Last?

It depends on the treatment as well as the quantity injected. Most treatments last 4-12 months depending on factors.