Platelet Rich Fibrin Matrix (PRFM) Hair Restoration in St. Louis, MO

If you’re experiencing thinning hair or early hair loss, you’ve likely come across a variety of potential solutions—from over-the-counter supplements and topical creams to surgical interventions like hair transplants. One minimally invasive option that’s growing in popularity is Platelet-Rich Fibrin Matrix (PRFM) hair restoration.

What is Platelet-Rich Fibrin Matrix (PRFM)?

Platelet-Rich Fibrin Matrix (PRFM) is a next-generation form of Platelet-Rich Plasma (PRP). Like PRP, PRFM is derived from your own blood and contains a high concentration of platelets. However, it goes a step further by incorporating a fibrin matrix that helps:

Protect and stabilize the platelets, allowing for a more controlled and sustained release of growth factors.

Enhance healing and regeneration processes for improved tissue growth.

In hair restoration, these concentrated platelets (and the growth factors they release) are used to stimulate hair follicles, potentially slowing down hair loss and encouraging new, healthier hair growth.

How is the PRFM Hair Restoration Process Done?

  • Blood Draw - The treatment begins with a standard blood draw, usually from a vein in your arm. The amount of blood taken is typically small, similar to what you would give during routine blood tests.
  • Centrifugation - The tube of blood is then placed in a specialized centrifuge. This process separates the red blood cells from the platelet-rich plasma and platelet-poor plasma.
  • Formation of the Fibrin Matrix - A unique step in PRFM preparation involves mixing in specific reagents that lead to the creation of a fibrin matrix. This matrix helps keep the platelets more stable and active for a longer duration.
  • Injection into the Scalp - The PRFM is carefully injected into areas of the scalp where hair is thinning or miniaturizing. The injections are done using small needles, and while some patients may feel mild discomfort, it is generally well-tolerated.
  • Post-Procedure Care - After the procedure, you can typically return to your regular activities immediately, though your practitioner may advise you to avoid strenuous activities or heavy hair treatments (coloring, harsh chemicals, etc.) for a short period.

What is PRFM Used For in Hair Restoration?

  • Thinning Hair: Early-stage hair loss in men and women can sometimes be stabilized or slowed, and the existing hair can become stronger and thicker.
  • Receding Hairlines: For individuals noticing a receding hairline, PRFM can be used to help regenerate healthier hair growth in targeted areas.
  • Boosting Overall Scalp Health: The growth factors in PRFM can help nourish the scalp, fostering an environment conducive to hair growth.

Who is a Candidate?

  • Men and Women: Anyone experiencing thinning hair or minor hair loss can be considered.
  • Early to Moderate Hair Loss: PRFM is most effective in the earlier stages of hair loss. Advanced baldness with dormant or inactive follicles may benefit more from surgical options.
  • Healthy Individuals: You should be in generally good health to ensure your body’s healing processes can support hair regeneration. Certain medical conditions or medications might need to be discussed with your provider to confirm your suitability.

Are There Any Side Effects?

Because PRFM is derived from your own blood, the risk of allergic reactions or complications is minimal. However, some side effects can occur due to the injection process:

  • Mild Scalp Discomfort or Tenderness
  • Redness or Swelling at Injection Sites
  • Bruising (though typically minor and temporary)
  • Itching or Tingling Sensations in the Treated Areas

These side effects usually resolve quickly. It’s essential to follow your provider’s aftercare instructions to minimize discomfort and ensure optimal results.

What Are the Benefits of PRFM Hair Restoration?

  • Minimally Invasive: PRFM involves simple injections, so there are no surgical incisions or extensive downtime.
  • Natural-Looking Results: Because you’re using your body’s own platelets, the hair growth that results is typically very natural in appearance.
  • Low Risk: PRFM is autologous (from your own blood), so there’s minimal risk of infection or allergic reaction.
  • Improved Scalpel Health: The growth factors not only target hair follicles but can also improve the health of the scalp.
  • Versatility: PRFM can be used as a standalone treatment or in conjunction with other therapies (such as microneedling or low-level laser therapy) to boost outcomes.

General Questions

  • How many sessions will I need? Most practitioners recommend a series of treatments (often three or more) spaced several weeks apart. After the initial series, maintenance sessions might be suggested every 6–12 months depending on individual results and hair loss patterns.
  • When will I see results? - Hair growth is a gradual process. Patients generally start noticing improvements in hair thickness and a reduction in shedding after about 3–6 months, with full effects visible around 9–12 months.
  • Is the treatment painful? Discomfort is typically mild. Some providers apply a topical numbing cream or use a local anesthetic to lessen any pain from the injections.
  • Can PRFM be combined with other hair restoration techniques? Yes. Many people combine PRFM with other therapies, such as topical hair growth products, low-level laser therapy, or hair transplant procedures, for more comprehensive results.
  • Are there any lifestyle changes I need to make? Generally, no major changes are needed. However, maintaining good overall health—through a balanced diet, regular exercise, and stress management—can significantly support the results. Avoiding smoking and minimizing alcohol intake can also help optimize scalp health.
  • Is PRFM the same as PRP? PRFM is often viewed as an enhanced version of PRP because of the added fibrin matrix. This fibrin structure can prolong the release of growth factors, making it potentially more effective.

Other Applicable Information

  • Consultation Is Key: A detailed consultation with one of The Saint Louis Med Spa’s nurse injectors is vital. They’ll evaluate your hair loss pattern, discuss realistic expectations, and determine the best treatment plan for you.
  • Long-Term Maintenance: Remember that hair loss is a progressive condition. Even if PRFM successfully stimulates hair regrowth, you may need maintenance treatments to preserve and optimize results.
  • Holistic Approach: Combining PRFM with lifestyle changes (stress reduction, a nutrient-rich diet, etc.) and possibly prescription medications (like finasteride for men or minoxidil) can further enhance and extend the benefits of the treatment.

Platelet-Rich Fibrin Matrix (PRFM) hair restoration offers a promising, minimally invasive option for those looking to combat thinning hair. With its ability to harness your body’s own growth factors and stabilize them within a fibrin matrix, PRFM may help slow down hair loss and improve hair quality over time. As always, it’s essential to seek out an experienced medical professional for a personalized assessment. With realistic expectations and proper care, PRFM can be an excellent addition to your hair restoration arsenal—helping you regain confidence and enjoy a healthier, fuller head of hair.

Benefits of Platelet Rich Fibrin Matrix (PRFM) Hair Restoration

  • Higher concentration of platelets: PRFM uses a specialized process to isolate and concentrate growth factors, potentially increasing the potency of each injection.
  • Slow release mechanism: The fibrin matrix prolongs the release of growth factors at the treatment site, which may support more consistent hair follicle stimulation over time.
  • Stimulation of dormant follicles: Growth factors in platelets can signal dormant hair follicles to re-enter an active growth phase.
  • Thicker, fuller hair: Patients often report increased thickness and volume, especially in areas of thinning hair.
  • Autologous treatment: Because PRFM uses your own blood, there is minimal risk of allergic reaction or adverse immune response.
  • Minimal downtime: Many individuals can resume normal daily activities immediately after the procedure. Mild tenderness or swelling at the injection sites can occur but typically resolves quickly.
Book My PRFM

Platelet Rich Fibrin Matrix (PRFM) Hair Restoration

Frequently Asked Questions

What Is PRFM?

PRFM stands for platelet-rich fibrin matrix, it uses platelets and natural growth factors taken from a patient's blood to rejuvenate their skin.

What Conditions Can PRFM Address?

PRFM is often used for facial rejuvenation and hair restoration.

Is PRFM Therapy Safe?

Yes. Because PRFM is derived from your own blood (autologous treatment), the risk of allergic reaction or rejection is extremely low.

How Many PRFM Sessions Are Needed?

Treatment protocols vary based on the condition being addressed, but most services range between 3-4 sessions.

When Will I See Results?

Typically 2-4 weeks for skin rejuvenation and 3-6 months for hair restoration.

How Long Do the Effects Last?

It depends on the treatment as well as the quantity injected. Most treatments last 4-12 months depending on factors.