
Microneedling with Platelet Rich Plasma (PRP) in St. Louis, MO
Microneedling with platelet-rich plasma (PRP)—sometimes referred to as the “vampire facial”—has become a popular treatment in the world of aesthetics and skincare. This minimally invasive procedure combines two powerful techniques to rejuvenate skin and address a variety of cosmetic concerns.
What Is Microneedling with PRP?
Microneedling is a procedure where a device containing tiny, sterile needles creates controlled micro-injuries (tiny punctures) in the skin’s surface. These micro-injuries prompt the body’s natural healing response, resulting in the production of new collagen and elastin—proteins essential for firm, supple skin.
PRP stands for Platelet-Rich Plasma. It’s derived from your own blood, which is drawn and then spun in a centrifuge to separate red blood cells from the platelets and plasma. This concentration of platelets is rich in growth factors, which help stimulate tissue repair and cell growth.
When PRP is applied to the skin after microneedling, it accelerates and amplifies the skin’s natural healing process, promoting faster cell renewal and enhancing the overall rejuvenation effect.
How Is the Procedure Performed?
- Consultation and Preparation - Before treatment, you’ll meet with a esthetician from The Saint Louis Med Spa to discuss your goals, skin concerns, and medical history. They will assess if you’re a suitable candidate.
- Blood Draw - A small amount of your blood is drawn (similar to a routine blood test). The sample is placed into a centrifuge, which separates the platelet-rich plasma from the other components of the blood.
- Skin Cleansing and Numbing - Your skin is cleansed to remove makeup, oils, and debris. A topical numbing cream is often applied to minimize discomfort during the microneedling process.
- Microneedling - A microneedling device is gently moved across the targeted area. The tiny needles create micro-channels in the skin, stimulating collagen production.
- Application of PRP - Right after microneedling, the PRP is applied to the treated skin. The growth factors in the PRP seep into the freshly created micro-channels, enhancing the body’s regenerative processes.
- Post-Treatment Care - A soothing serum or balm may be applied, and you’ll receive aftercare instructions (e.g., avoiding direct sun exposure, abstaining from harsh skincare products, and keeping the area clean).
How Does It Work?
Microneedling stimulates the skin’s natural healing response by creating controlled injuries. These micro-injuries signal the body to produce more collagen and elastin. Meanwhile, the PRP’s growth factors further support and speed up tissue repair and cell regeneration. This synergy leads to:
- Improved skin texture
- Reduced appearance of fine lines and wrinkles
- Refined pores
- Less noticeable acne scars and other types of scars
- Enhanced overall skin radiance
What Is It Used For?
- Fine Lines and Wrinkles - Microneedling with PRP helps soften the appearance of early signs of aging, such as crow’s feet and smile lines.
- Acne Scars - The boost in collagen production can help smooth out acne scars and other forms of scarring.
- Uneven Skin Tone and Texture - If you struggle with mild hyperpigmentation, rough texture, or large pores, this procedure can help minimize these concerns.
- Skin Rejuvenation - Individuals looking for an overall skin refresh—improved firmness, elasticity, and glow can benefit from this treatment.
Who Is a Candidate?
- Healthy Individuals: Generally, anyone in good health seeking to address mild to moderate skin concerns may be a candidate.
- Non-Smokers: Smoking can affect blood circulation and may reduce the effectiveness of the PRP treatment.
- Realistic Expectations: Those who understand that results are gradual and may require multiple sessions typically see the best outcomes.
- No Active Skin Infections or Severe Acne: It’s best to treat active skin conditions first before trying microneedling with PRP.
- If you have a history of certain medical issues (e.g., blood disorders, autoimmune diseases), are pregnant, or use certain medications, consult your healthcare provider to ensure this treatment is safe for you.
Potential Side Effects
Microneedling with PRP is generally considered safe, but like any cosmetic procedure, it comes with some possible side effects:
- Redness and Mild Swelling: Common immediately following the treatment, usually resolving within a day or two.
- Bruising: Some bruising can occur at the blood draw site or around the treated area (though it is usually mild).
- Dryness or Flaking: As the skin heals, some dryness or flaking may occur.
- Sensitivity or Discomfort: You may experience tingling or tenderness.
- Risk of Infection: Rare, but possible if proper aftercare instructions aren’t followed.
Benefits of Microneedling with PRP
- Increased Collagen Production: Helps keep skin looking youthful and firm.
- Improved Skin Texture: Leads to a smoother, more refined skin surface.
- Reduced Appearance of Scars and Wrinkles: Encourages the skin to repair itself from the inside out.
- Natural Approach: Because PRP is derived from your own blood, the risk of allergic reaction or adverse effects is minimized.
- Minimal Downtime: Many people return to normal activities within a day or two, depending on the intensity of the treatment.
General Questions
- How many sessions do I need? Most individuals benefit from a series of 3–6 treatments spaced about 4–6 weeks apart. However, the exact number of sessions depends on your skin concerns and goals.
- When will I see results? You may notice an immediate “glow” post-treatment, but collagen remodeling takes time. Many people see more significant improvements around 2–4 weeks after their first session, with continued enhancement for several months.
- Is microneedling with PRP painful? A topical numbing cream is usually applied, so discomfort is generally minimal. Some people describe it as a mild prickling sensation.
- Are there any pre-treatment precautions? Avoid sun exposure, retinol products, and certain skin treatments (like chemical peels) for a few days before your appointment. Your provider will give you specific instructions.
- Can I wear makeup after the procedure? It’s best to avoid makeup for at least 24 hours post-treatment to allow the skin to heal and reduce the risk of infection.
- Is microneedling with PRP safe for darker skin tones? Yes, microneedling with PRP is generally considered safe for most skin tones because it doesn’t rely on heat (like lasers do). However, always consult a qualified professional to ensure the technique and needle depth are appropriate for your skin type.
Additional Tips and Information
- Aftercare: Avoid direct sun exposure and use a broad-spectrum sunscreen with SPF 30 or higher. Stay hydrated and follow your practitioner’s guidelines for skincare products and activities. Refrain from using harsh exfoliants, retinoids, or other potent skincare products immediately after the procedure.
- Maintenance: Periodic maintenance treatments may be recommended to sustain collagen production and keep skin looking its best.
Microneedling with PRP can be an excellent option for individuals looking to improve skin texture, reduce signs of aging, and promote an overall more radiant complexion—using the body’s own healing mechanisms. With minimal downtime, natural components, and versatile applications, this treatment continues to grow in popularity. As always, consult with one of The Saint Louis Med Spa’s estheticians to determine whether microneedling with PRP is right for your unique skin concerns and aesthetic goals.

Benefits of Microneedling with PRP
- Enhanced Collagen Production - Collagen is the protein responsible for firm, plump skin. The combination of microneedling’s controlled injury plus the growth factors in PRP amplifies collagen production, leading to a smoother, more youthful complexion over time.
- Reduced Appearance of Scars and Fine Lines - This therapy is often used to help improve acne scars, surgical scars, and signs of aging such as fine lines and wrinkles. The skin’s natural repair process helps resurface irregularities and refine skin texture.
- Minimized Pore Size and Smoother Texture - Many people notice tighter pores and an overall smoother skin texture. The collagen boost not only improves elasticity but can reduce the prominence of pores.
- Improved Skin Tone and Pigmentation - By promoting cell turnover and healthy tissue growth, microneedling with PRP can address hyperpigmentation, uneven skin tone, and sun damage, giving the skin a more uniform look.
- Accelerated Healing and Reduced Downtime - PRP is known for its healing properties. The addition of platelets speeds up the recovery process post-microneedling, helping diminish redness or irritation more quickly.
- Natural and Safe - Since PRP is derived from your own blood, the risk of an adverse or allergic reaction is minimal. Patients appreciate that this is an all-natural approach to skin rejuvenation.
- Versatile Treatment Areas - While most common on the face and neck, microneedling with PRP can also be used on areas like the décolletage, hands, and even the scalp for hair restoration purposes.
Microneedling with Platelet Rich Plasma (PRP)
Frequently Asked Questions
What Is PRP?
Platelet-Rich Plasma (PRP) is a concentrated solution of platelets derived from your own blood. Platelets contain growth factors and proteins that can help stimulate tissue healing, decrease inflammation, and support regenerative processes when injected into a target area.
What is SkinPen Microneedling?
SkinPen is a medical-grade, FDA-cleared microneedling device used to create controlled micro-injuries in the skin’s surface. These tiny punctures help stimulate the body’s natural wound-healing process, boosting collagen and elastin production. As a result, it can improve skin texture, reduce the appearance of fine lines, wrinkles, and scars, and promote a smoother, more even complexion.
Is It Safe For All Skin Types?
Yes. SkinPen is considered suitable for all Fitzpatrick skin types (I-VI). Unlike some laser treatments, which carry a higher risk of pigmentation issues in darker skin tones, microneedling is generally safe for everyone. However, a consultation is essential to determine if the treatment is right for your specific concerns.
Is PRP Therapy Safe?
Yes. Because PRP is derived from your own blood (autologous treatment), the risk of allergic reaction or rejection is extremely low.
How Many PRP Sessions Are Needed?
Treatment protocols vary based on the condition being addressed, but most services range between 3-4 sessions.
When Will I See Results?
Typically 2-4 weeks for skin rejuvenation and 3-6 months for hair restoration.
How Long Do the Effects Last?
It depends on the treatment as well as the quantity injected. Most treatments last 4-12 months depending on factors.
Can PRP Be Combined with Other Treatments?
Yes. It is often combined with microneedling, laser treatments, and many other services.